Determinants of cardiac autonomic dysfunction in ESRD.

ABSTRACT:

Background and objectives

Cardiovascular events are common in patients with ESRD. Whether sympathetic overactivity or vagal withdrawal contribute to cardiovascular events is unclear. We determined the general prevalence and clinical correlates of heart rate variability in patients on hemodialysis.

Design, setting, participants, & measurements

We collected baseline information on demographics, clinical conditions, laboratory values, medications, physical performance, left ventricular mass (LVM), and 24-hour Holter monitoring on 239 subjects enrolled in the Frequent Hemodialysis Network Daily Trial.

Results

The mean R-R interval was 812 ± 217 ms. The SD of R-R intervals was 79.1 ± 40.3 ms. Spectral power analyses showed low-frequency (sympathetic modulation of heart rat

SUBMITTER: Chan CT 

PROVIDER: S-EPMC2974383 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature