Microarray data integration for genome-wide analysis of human tissue-selective gene expression.

ABSTRACT:

Background

Microarray gene expression data are accumulating in public databases. The expression profiles contain valuable information for understanding human gene expression patterns. However, the effective use of public microarray data requires integrating the expression profiles from heterogeneous sources.

Results

In this study, we have compiled a compendium of microarray expression profiles of various human tissue samples. The microarray raw data generated in different research laboratories have been obtained and combined into a single dataset after data normalization and transformation. To demonstrate the usefulness of the integrated microarray data for studying human gene expression patterns, we have analyzed the dataset to identify potential tissue-selective genes. A n

SUBMITTER: Wang L 

PROVIDER: S-EPMC2975411 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature