The role of sigma factor RpoH1 in the pH stress response of Sinorhizobium meliloti.

ABSTRACT:

Background

Environmental pH stress constitutes a limiting factor for S. meliloti survival and development. The response to acidic pH stress in S. meliloti is versatile and characterized by the differential expression of genes associated with various cellular functions. The purpose of this study was to gain detailed insight into the participation of sigma factors in the complex stress response system of S. meliloti 1021 using pH stress as an effector.

Results

In vitro assessment of S meliloti wild type and sigma factor mutants provided first evidence that the sigma factor RpoH1 plays a major role in the pH stress response. Differential expression of genes related to rhizobactin biosynthesis was observed in microarray analyses performed with the rpoH1 mutant at pH 7.0. The inv

SUBMITTER: de Lucena DK 

PROVIDER: S-EPMC2976971 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature