4-Butyl-1-(2,3,4-tri-O-acetyl-β-l-fuco-pyranos-yl)-1H-1,2,3-triazole.

ABSTRACT: The title compound, C(18)H(27)N(3)O(7), was synthesized by Cu(I)-catalysed coupling of an azide with an alkyne as part of a study into the synthesis of N-glycosyl-1,2,3-triazoles. The crystal structure confirms the selective formation of the β-conformer of the pyran-ose N-glycoside, thus confirming the retention of stereochemistry during heterocycle formation with the N-glycosyl triazole group occupying the equatorial position at the anomeric C atom. The structure exhibits two crystallographically independent mol-ecules (A and B) with essentially identical conformations with a weighted r.m.s. deviation of only 0.09 Å. The mol-ecules are arranged in layers with hydro-phobic and more polar sections built from the butyl triazole units on the one hand and the more polar moieties dominated by t

SUBMITTER: Alhassan AB 

PROVIDER: S-EPMC2977263 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature