Indirect comparisons: a review of reporting and methodological quality.

ABSTRACT:

Background

The indirect comparison of two interventions can be valuable in many situations. However, the quality of an indirect comparison will depend on several factors including the chosen methodology and validity of underlying assumptions. Published indirect comparisons are increasingly more common in the medical literature, but as yet, there are no published recommendations of how they should be reported. Our aim is to systematically review the quality of published indirect comparisons to add to existing empirical data suggesting that improvements can be made when reporting and applying indirect comparisons.

Methodology/findings

Reviews applying statistical methods to indirectly compare the clinical effectiveness of two interventions using randomised controlled trials we

SUBMITTER: Donegan S 

PROVIDER: S-EPMC2978085 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature