Unusual duplication of the insulin-like receptor in the crustacean Daphnia pulex.

ABSTRACT:

Background

The insulin signaling pathway (ISP) has a key role in major physiological events like carbohydrate metabolism and growth regulation. The ISP has been well described in vertebrates and in a few invertebrate model organisms but remains largely unexplored in non-model invertebrates. This study is the first detailed genomic study of this pathway in a crustacean species, Daphnia pulex.

Results

The Daphnia pulex draft genome sequence assembly was scanned for major components of the ISP with a special attention to the insulin-like receptor. Twenty three putative genes are reported. The pathway appears to be generally well conserved as genes found in other invertebrates are present. Major findings include a lower number of insulin-like peptides in Daphnia as compared to o

SUBMITTER: Boucher P 

PROVIDER: S-EPMC2978223 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature