Results from the National Sepsis Practice Survey: use of drotrecogin α (activated) and other therapeutic decisions.

ABSTRACT:

Purpose

We sought to evaluate factors associated with choices about provided care for patients with septic shock, including the use of drotrecogin α (activated) (DAA).

Materials and methods

We administered a mail-based survey to a random sample of intensivists. Study vignettes presented patients with septic shock with identical severity of illness scores but different ages, body mass indices, and comorbidities. Respondents estimated outcomes and selected care beyond standardized initial care (eg, antibiotics) for each hypothetical patient.

Results

For most vignettes (99.1%), respondents added care, most commonly low tidal volume ventilation (87.6%) and enteral nutrition (73.3%). Choosing to administer DAA was not associated with predictions about mortality or bleeding

SUBMITTER: O'Brien JM 

PROVIDER: S-EPMC2978258 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature