Topographical frequency dynamics within EEG and MEG sleep spindles.

ABSTRACT:

Objective

Spindles are rhythmic bursts of 10-16 Hz activity, lasting ∼1 s, occur during normal stage 2 sleep. Spindles are slower in frontal EEG and possibly MEG. The posterior-fast EEG pattern may predominate early in the spindle, and the anterior-slow pattern late. We aimed to determine the proportion of spindles showing this spatio-spectro-temporal interaction for EEG, and whether it occurs in MEG.

Methods

We recorded high density EEG and MEG from seven healthy subjects during normal stage 2 sleep. High vs. low frequency (12 vs. 14 Hz) power was measured early vs. late (25th-45th vs. 55th-75th duration percentile) in 183 spindle discharges.

Results

The predicted spatio-spectro-temporal interaction was shown by 48% of EEG and 34% of MEG spindles (chance=25%). Topogr

SUBMITTER: Dehghani N 

PROVIDER: S-EPMC2978261 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature