PALI-a database of Phylogeny and ALIgnment of homologous protein structures.

ABSTRACT: PALI (release 1.2) contains three-dimensional (3-D) structure-dependent sequence alignments as well as structure-based phylogenetic trees of homologous protein domains in various families. The data set of homologous protein structures has been derived by consulting the SCOP database (release 1.50) and the data set comprises 604 families of homologous proteins involving 2739 protein domain structures with each family made up of at least two members. Each member in a family has been structurally aligned with every other member in the same family (pairwise alignment) and all the members in the family are also aligned using simultaneous super-position (multiple alignment). The structural alignments are performed largely automatically, with manual interventions especially in the cases of distan

SUBMITTER: Balaji S 

PROVIDER: S-EPMC29825 | biostudies-literature | 2001 Jan

REPOSITORIES: biostudies-literature