New directions in childhood obesity research: how a comprehensive biorepository will allow better prediction of outcomes.

ABSTRACT:

Background

Childhood obesity is associated with the early development of diseases such as type 2 diabetes and cardiovascular disease. Unfortunately, to date, traditional methods of research have failed to identify effective prevention and treatment strategies, and large numbers of children and adolescents continue to be at high risk of developing weight-related disease.

Aim

To establish a unique 'biorepository' of data and biological samples from overweight and obese children, in order to investigate the complex 'gene × environment' interactions that govern disease risk.

Methods

The 'Childhood Overweight BioRepository of Australia' collects baseline environmental, clinical and anthropometric data, alongside storage of blood samples for genetic, metabolic and hormonal

SUBMITTER: Sabin MA 

PROVIDER: S-EPMC2984501 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature