Entomologic and molecular investigation into Plasmodium vivax transmission in Singapore, 2009.

ABSTRACT:

Background

Singapore has been certified malaria free since November 1982 by the World Health Organization and despite occasional local transmission, the country has maintained the standing. In 2009, three clusters of malaria cases were reported in Singapore.

Methods

Epidemiological, entomological and molecular studies were carried out to investigate the three clusters, namely Mandai-Sungei Kadut, Jurong Island and Sembawang.

Results

A total of 29 malaria patients, with no recent travel history, were reported in the three clusters. Molecular analysis based on the msp3α and msp1 genes showed two independent local transmissions: one in Mandai-Sungei Kadut and another in Sembawang. Almost all cases within each cluster were epidemiologically linked. In Jurong Island cluste

SUBMITTER: Ng LC 

PROVIDER: S-EPMC2988040 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature