Prevalence of seroprotection against the pandemic (H1N1) virus after the 2009 pandemic.

ABSTRACT:

Background

Before pandemic (H1N1) 2009, less than 10% of serum samples collected from all age groups in the Lower Mainland of British Columbia, Canada, showed seroprotection against the pandemic (H1N1) 2009 virus, except those from very elderly people. We reassessed this profile of seroprotection by age in the same region six months after the fall 2009 pandemic and vaccination campaign.

Methods

We evaluated 100 anonymized serum samples per 10-year age group based on convenience sampling. We measured levels of antibody against the pandemic virus by hemagglutination inhibition and microneutralization assays. We assessed geometric mean titres and the proportion of people with seroprotective antibody levels (hemagglutination inhibition titre ≥ 40). We performed sensitivity analy

SUBMITTER: Skowronski DM 

PROVIDER: S-EPMC2988533 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature