Application of alternative models to identify QTL for growth traits in an F2 Duroc x Pietrain pig resource population.

ABSTRACT:

Background

A variety of analysis approaches have been applied to detect quantitative trait loci (QTL) in experimental populations. The initial genome scan of our Duroc x Pietrain F2 resource population included 510 F2 animals genotyped with 124 microsatellite markers and analyzed using a line-cross model. For the second scan, 20 additional markers on 9 chromosomes were genotyped for 954 F2 animals and 20 markers used in the first scan were genotyped for 444 additional F2 animals. Three least-squares Mendelian models for QTL analysis were applied for the second scan: a line-cross model, a half-sib model, and a combined line-cross and half-sib model.

Results

In total, 26 QTL using the line-cross model, 12 QTL using the half-sib model and 3 additional QTL using the combined lin

SUBMITTER: Choi I 

PROVIDER: S-EPMC2989936 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature