Fully automated system for the quantification of human osteoarthritic knee joint effusion volume using magnetic resonance imaging.

ABSTRACT:

Introduction

Joint effusion is frequently associated with osteoarthritis (OA) flare-up and is an important marker of therapeutic response. This study aimed at developing and validating a fully automated system based on magnetic resonance imaging (MRI) for the quantification of joint effusion volume in knee OA patients.

Methods

MRI examinations consisted of two axial sequences: a T2-weighted true fast imaging with steady-state precession and a T1-weighted gradient echo. An automated joint effusion volume quantification system using MRI was developed and validated (a) with calibrated phantoms (cylinder and sphere) and effusion from knee OA patients; (b) with assessment by manual quantification; and (c) by direct aspiration. Twenty-five knee OA patients with joint effusion were

SUBMITTER: Li W 

PROVIDER: S-EPMC2991000 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature