Prediction of ESRD and death among people with CKD: the Chronic Renal Impairment in Birmingham (CRIB) prospective cohort study.

ABSTRACT:

Background

Validated prediction scores are required to assess the risks of end-stage renal disease (ESRD) and death in individuals with chronic kidney disease (CKD).

Study design

Prospective cohort study with validation in a separate cohort.

Setting & participants

Cox regression was used to assess the relevance of baseline characteristics to risk of ESRD (mean follow-up, 4.1 years) and death (mean follow-up, 6.0 years) in 382 patients with stages 3-5 CKD not initially on dialysis therapy in the Chronic Renal Impairment in Birmingham (CRIB) Study. Resultant risk prediction equations were tested in a separate cohort of 213 patients with CKD (the East Kent cohort).

Factors

44 baseline characteristics (including 30 blood and urine assays).

Outcomes

ESRD and

SUBMITTER: Landray MJ 

PROVIDER: S-EPMC2991589 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature