Four diphenylpropanes and a cycloheptadibenzofuran from Bussea sakalava from the Madagascar dry forest.

ABSTRACT: Investigation of the endemic Malagasy plant Bussea sakalava for antiproliferative activity against the A2780 ovarian cancer cell line led to the isolation of the four new diphenylpropanes 1-4 and the new cycloheptadibenzofuran 5; compound 5 has a previously unreported natural product skeleton. The structure elucidation of these compounds was based on the analysis of their 1D and 2D NMR and mass spectroscopic data. Compounds 1-5 were tested for antiproliferative activity against the A2780 human ovarian cancer cell line.

SUBMITTER: Pan E 

PROVIDER: S-EPMC2993851 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature