Geographical variation in cardiovascular incidence: results from the British Women's Heart and Health Study.

ABSTRACT:

Background

Prevalence of cardiovascular disease (CVD) in women shows regional variations not explained by common risk factors. Analysis of CVD incidence will provide insight into whether there is further divergence between regions with increasing age.

Methods

Seven-year follow-up data on 2685 women aged 59-80 (mean 69) at baseline from 23 towns in the UK were available from the British Women's Heart and Health Study. Time to fatal or non-fatal CVD was analyzed using Cox regression with adjustment for risk factors, using multiple imputation for missing values.

Results

Compared to South England, CVD incidence is similar in North England (HR 1.05 (95% CI 0.84, 1.31)) and Scotland (0.93 (0.68, 1.27)), but lower in Midlands/Wales (0.85 (0.64, 1.12)). Event severity influen

SUBMITTER: Kim LG 

PROVIDER: S-EPMC2996371 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature