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ABSTRACT: Purpose
To investigate the retinal structure and function during the progression of X-linked retinoschisis (XLRS) from childhood to adulthood.Methods
Ten patients clinically diagnosed with XLRS were investigated at 6-15 years of age (mean age 9 years) with a follow-up 8 to 14 years later (mean 12 years). The patients underwent regular ophthalmic examination as well as testing of best corrected visual acuity (BCVA), visual field (VF) and assessment of full-field electroretinography (ERG) during their first visit. During the follow-up, the same clinical protocols were repeated. In addition, macular structure and function was examined with multifocal electroretinography (mfERG) and optical coherence tomography (OCT). The patients were 18-25 years of age (mean age 21 years) at
SUBMITTER: Kjellstrom S
PROVIDER: S-EPMC2997439 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature