Stopping smokeless tobacco with varenicline: randomised double blind placebo controlled trial.

ABSTRACT:

Objective

To assess the efficacy and safety of varenicline (a licensed cigarette smoking cessation aid) in helping users of smokeless tobacco to quit.

Design

Double blind, placebo controlled, parallel group, multicentre, randomised controlled trial.

Setting

Medical clinics (mostly primary care) in Norway and Sweden.

Participants

Men and women aged ≥18 who used smokeless tobacco at least eight times a day, with no abstinence period over three months within one year before screening, who wanted to quit all tobacco use. Participants were excluded if they used any other form of tobacco (except smokeless tobacco) or medication to stop smoking within three months of screening or had any pre-existing medical or psychiatric condition.

Interventions

Varenicline 1

SUBMITTER: Fagerstrom K 

PROVIDER: S-EPMC2997603 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature