Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease.

ABSTRACT:

Background

Incident anxiety and depression are associated separately with cardiac events and mortality in patients after acute coronary syndromes, but the influence of persistent comorbid depression and anxiety on mortality remains unknown. The purpose of this study was to determine the prevalence of comorbid persistent depressive and anxious symptoms in individuals with ischemic heart disease and to evaluate effects on mortality.

Methods

Prospective, longitudinal cohort design in the context of a randomized trial to decrease patient delay in seeking treatment for ischemic heart symptoms (PROMOTION trial) was used, with twelve-month follow-up of 2325 individuals with stable ischemic heart disease. Participants were assessed on enrollment and at 3 months using the Multiple Ad

SUBMITTER: Doering LV 

PROVIDER: S-EPMC2998562 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature