Ontology highlight
ABSTRACT:
SUBMITTER: Levy D
PROVIDER: S-EPMC2998712 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Nature genetics 20090510 6
Blood pressure is a major cardiovascular disease risk factor. To date, few variants associated with interindividual blood pressure variation have been identified and replicated. Here we report results of a genome-wide association study of systolic (SBP) and diastolic (DBP) blood pressure and hypertension in the CHARGE Consortium (n = 29,136), identifying 13 SNPs for SBP, 20 for DBP and 10 for hypertension at P < 4 × 10(-7). The top ten loci for SBP and DBP were incorporated into a risk score; me ...[more]