Prognostic importance of hyponatremia in patients with acute pulmonary embolism.

ABSTRACT:

Rationale

Although associated with adverse outcomes in other cardiopulmonary conditions, the prognostic value of hyponatremia, a marker of neurohormonal activation, in patients with acute pulmonary embolism (PE) is unknown.

Objectives

To examine the associations between hyponatremia and mortality and hospital readmission rates for patients hospitalized with PE.

Methods

We evaluated 13,728 patient discharges with a primary diagnosis of PE from 185 hospitals in Pennsylvania (January 2000 to November 2002). We used random-intercept logistic regression to assess the independent association between serum sodium levels at the time of presentation and mortality and hospital readmission within 30 days, adjusting for patient (race, insurance, severity of illness, use of thromb

SUBMITTER: Scherz N 

PROVIDER: S-EPMC3001260 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature