Serum adipocyte fatty acid-binding protein, retinol-binding protein 4, and adiponectin concentrations in relation to the development of the metabolic syndrome in Korean boys: a 3-y prospective cohort study.

ABSTRACT:

Background

Adipocyte fatty acid-binding protein (A-FABP), retinol-binding protein 4 (RBP4), and adiponectin have been associated with insulin resistance and the metabolic syndrome in adults.

Objective

We evaluated the association of A-FABP, RBP4, and adiponectin with the metabolic syndrome in Korean boys.

Design

In this prospective cohort study, 159 boys participated in a school-based health examination and were followed up after 3 y. The metabolic syndrome in children was defined by using the pediatric adaptation of the National Cholesterol Education Program criteria.

Results

Compared with normal-weight participants, overweight children had significantly higher A-FABP (23.6 ± 8.2 compared with 12.8 ± 5.1 μg/L, P < 0.001) and RBP4 (69.3 ± 17.1 compared with 59.

SUBMITTER: Choi KM 

PROVIDER: S-EPMC3001596 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature