The pathogenesis of low pathogenicity H7 avian influenza viruses in chickens, ducks and turkeys.

ABSTRACT:

Background

Avian influenza (AI) viruses infect numerous avian species, and low pathogenicity (LP) AI viruses of the H7 subtype are typically reported to produce mild or subclinical infections in both wild aquatic birds and domestic poultry. However relatively little work has been done to compare LPAI viruses from different avian species for their ability to cause disease in domestic poultry under the same conditions. In this study twelve H7 LPAI virus isolates from North America were each evaluated for their comparative pathogenesis in chickens, ducks, and turkeys.

Results

All 12 isolates were able to infect all three species at a dose of 106 50% egg infectious doses based on seroconversion, although not all animals seroconverted with each isolate-species combination. The se

SUBMITTER: Spackman E 

PROVIDER: S-EPMC3002305 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature