Final adult height of children with inflammatory bowel disease is predicted by parental height and patient minimum height Z-score.

ABSTRACT:

Background

This study was designed to elucidate the contribution of parental height to the stature of children with inflammatory bowel disease (IBD), who often exhibit growth impairment. Accordingly, we compared patients' final adult heights and target heights based on measured parental heights and examined predictors of final adult height in pediatric IBD patients.

Methods

We prospectively analyzed the growth of 295 patients diagnosed between ages 1 and 18 (211 Crohn's disease [CD], 84 ulcerative colitis [UC]) and their family members (283 mothers, 231 fathers, 55 siblings).

Results

Twenty-two percent had growth impairment (height for age Z-score <-1.64, equivalent to <5th percentile on growth curve) in more than 1 measurement since diagnosis; most growth-impaired pa

SUBMITTER: Lee JJ 

PROVIDER: S-EPMC3005189 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature