Blood pressure and cardiovascular disease risk in the Veterans Affairs Diabetes Trial.

ABSTRACT:

Objective

Blood pressure ranges associated with cardiovascular disease (CVD) events in advanced type 2 diabetes are not clear. Our objective was to determine whether baseline and follow-up (On-Study) systolic blood pressure (SBP), diastolic blood pressure (DBP), and SBP combined with DBP predict CVD events in the Veterans Affairs Diabetes Trial (VADT).

Research design and methods

Participants in the VADT (n = 1,791) with hypertension received stepped treatment to maintain blood pressure below the target of 130/80 mmHg in standard and intensive glycemic treatment groups. Blood pressure levels of all subjects at baseline and On-Study were analyzed to detect associations with CVD risk. The primary outcome was the time from randomization to the first occurrence of myocardial inf

SUBMITTER: Anderson RJ 

PROVIDER: S-EPMC3005453 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature