Common and drug-specific genetic influences on subjective effects to alcohol, tobacco and marijuana use.

ABSTRACT:

Aim

To examine variation in positive and negative subjective effects to alcohol, tobacco and marijuana and covariation between these three drugs and each effect.

Design

Retrospective self-reports of subjective effects were collected to estimate the genetic and environmental influences and the extent of their specificity across three drugs.

Participants

Data were drawn from 1299 adolescent and young adult same- and opposite sex twin- and sibling-pairs participating in the Colorado Center for Antisocial Drug Dependence (CADD).

Setting

A large, collaborative, longitudinal study of substance use and antisocial behavior in community and clinical adolescents.

Measurement

  Subjective effects were assessed using a 13-item questionnaire that included positive an

SUBMITTER: Haberstick BC 

PROVIDER: S-EPMC3006038 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature