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Quantifying the spatial dimension of dengue virus epidemic spread within a tropical urban environment.


ABSTRACT:

Background

Dengue infection spread in naive populations occurs in an explosive and widespread fashion primarily due to the absence of population herd immunity, the population dynamics and dispersal of Ae. aegypti, and the movement of individuals within the urban space. Knowledge on the relative contribution of such factors to the spatial dimension of dengue virus spread has been limited. In the present study we analyzed the spatio-temporal pattern of a large dengue virus-2 (DENV-2) outbreak that affected the Australian city of Cairns (north Queensland) in 2003, quantified the relationship between dengue transmission and distance to the epidemic's index case (IC), evaluated the effects of indoor residual spraying (IRS) on the odds of dengue infection, and generated recommendations f

SUBMITTER: Vazquez-Prokopec GM 

PROVIDER: S-EPMC3006131 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature