Origin and post-glacial dispersal of mitochondrial DNA haplogroups C and D in northern Asia.

ABSTRACT: More than a half of the northern Asian pool of human mitochondrial DNA (mtDNA) is fragmented into a number of subclades of haplogroups C and D, two of the most frequent haplogroups throughout northern, eastern, central Asia and America. While there has been considerable recent progress in studying mitochondrial variation in eastern Asia and America at the complete genome resolution, little comparable data is available for regions such as southern Siberia--the area where most of northern Asian haplogroups, including C and D, likely diversified. This gap in our knowledge causes a serious barrier for progress in understanding the demographic pre-history of northern Eurasia in general. Here we describe the phylogeography of haplogroups C and D in the populations of northern and eastern Asia. W

SUBMITTER: Derenko M 

PROVIDER: S-EPMC3006427 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature