Clinical effectiveness of elective single versus double embryo transfer: meta-analysis of individual patient data from randomised trials.

ABSTRACT:

Objective

To compare the effectiveness of elective single embryo transfer versus double embryo transfer on the outcomes of live birth, multiple live birth, miscarriage, preterm birth, term singleton birth, and low birth weight after fresh embryo transfer, and on the outcomes of cumulative live birth and multiple live birth after fresh and frozen embryo transfers.

Design

One stage meta-analysis of individual patient data.

Data sources

A systematic review of English and non-English articles from Medline, Embase, and the Cochrane Central Register of Controlled Trials (up to 2008). Additional studies were identified by contact with clinical experts and searches of bibliographies of all relevant primary articles. Search terms included embryo transfer, randomised controlled

SUBMITTER: McLernon DJ 

PROVIDER: S-EPMC3006495 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature