C-B4-02: Determining Genetic Risk Factors for Post- Hospitalization development of Deep-Vein Thrombosis

ABSTRACT: Background: Venothromboembolism (VTE) including deep venous thrombosis (DVT) and pulmonary embolism (PE) are significant health care problems. A highly specific DVT risk stratification model requires a combination of genetic, environmental, clinical, laboratory and radiographic measurements. Genetic factors associated with DVT in post-hospitalized medical and surgical patients are incompletely understood. Aim: Using the Personalized Medicine Research Project (PMRP) population and a limited number of disease associated polymorphisms were used to determine whether these markers were associated with DVT in the post-hospitlalization period. Methods: Marshfield Clinic patients who have experienced a DVT between 1999 and 2007 enrolled in the PMRP were genotyped for 52 disease associated polymorp

SUBMITTER: Cross D 

PROVIDER: S-EPMC3006593 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature