RLS in middle aged women and attention deficit/hyperactivity disorder in their offspring.

ABSTRACT:

Background

Previous studies have suggested that attention deficit/hyperactivity disorder (ADHD) and restless legs syndrome (RLS) could share some common genetic backgrounds, but the effect of these genetic components could be modest. To test this hypothesis, we conducted a large-scaled cross-sectional study to examine whether women with a child with ADHD had a higher risk of having RLS than women of unaffected children.

Methods

We included 65,554 women free of diabetes, arthritis, and pregnancy in the current analyses. Information on RLS was assessed using a set of standardized questions. Participants were considered to have RLS if they met four RLS diagnostic criteria recommended by the International RLS Study Group and had restless legs ≥5 times/month. Information on ADHD

SUBMITTER: Gao X 

PROVIDER: S-EPMC3008213 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature