Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease.

ABSTRACT:

Context

Hypertension guidelines advocate treating systolic blood pressure (BP) to less than 130 mm Hg for patients with diabetes mellitus; however, data are lacking for the growing population who also have coronary artery disease (CAD).

Objective

To determine the association of systolic BP control achieved and adverse cardiovascular outcomes in a cohort of patients with diabetes and CAD.

Design, setting, and patients

Observational subgroup analysis of 6400 of the 22,576 participants in the International Verapamil SR-Trandolapril Study (INVEST). For this analysis, participants were at least 50 years old and had diabetes and CAD. Participants were recruited between September 1997 and December 2000 from 862 sites in 14 countries and were followed up through March 2003 wi

SUBMITTER: Cooper-DeHoff RM 

PROVIDER: S-EPMC3008411 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature