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Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192.

ABSTRACT: Spirochaeta thermophila is a thermophilic, free-living anaerobe that is able to degrade various ?- and ?-linked sugar polymers, including cellulose. We report here the complete genome sequence of S. thermophila DSM 6192, which is the first genome sequence of a thermophilic, free-living member of the Spirochaetes phylum. The genome data reveal a high density of genes encoding enzymes from more than 30 glycoside hydrolase families, a noncellulosomal enzyme system for (hemi)cellulose degradation, and indicate the presence of a novel carbohydrate-binding module.

SUBMITTER: Angelov A 

PROVIDER: S-EPMC3008529 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature

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Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192.

Angelov Angel A   Liebl Susanne S   Ballschmiter Meike M   Bömeke Mechthild M   Lehmann Rüdiger R   Liesegang Heiko H   Daniel Rolf R   Liebl Wolfgang W  

Journal of bacteriology 20101008 24

Spirochaeta thermophila is a thermophilic, free-living anaerobe that is able to degrade various α- and β-linked sugar polymers, including cellulose. We report here the complete genome sequence of S. thermophila DSM 6192, which is the first genome sequence of a thermophilic, free-living member of the Spirochaetes phylum. The genome data reveal a high density of genes encoding enzymes from more than 30 glycoside hydrolase families, a noncellulosomal enzyme system for (hemi)cellulose degradation, a  ...[more]

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