Combined optical and X-ray tomosynthesis breast imaging.

ABSTRACT:

Purpose

To explore the optical and physiologic properties of normal and lesion-bearing breasts by using a combined optical and digital breast tomosynthesis (DBT) imaging system.

Materials and methods

Institutional review board approval and patient informed consent were obtained for this HIPAA-compliant study. Combined optical and tomosynthesis imaging analysis was performed in 189 breasts from 125 subjects (mean age, 56 years ± 13 [standard deviation]), including 138 breasts with negative findings and 51 breasts with lesions. Three-dimensional (3D) maps of total hemoglobin concentration (Hb(T)), oxygen saturation (So(2)), and tissue reduced scattering coefficients were interpreted by using the coregistered DBT images. Paired and unpaired t tests were performed between variou

SUBMITTER: Fang Q 

PROVIDER: S-EPMC3009384 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature