Reconstruction and analysis of genome-scale metabolic model of a photosynthetic bacterium.

ABSTRACT:

Background

Synechocystis sp. PCC6803 is a cyanobacterium considered as a candidate photo-biological production platform--an attractive cell factory capable of using CO2 and light as carbon and energy source, respectively. In order to enable efficient use of metabolic potential of Synechocystis sp. PCC6803, it is of importance to develop tools for uncovering stoichiometric and regulatory principles in the Synechocystis metabolic network.

Results

We report the most comprehensive metabolic model of Synechocystis sp. PCC6803 available, iSyn669, which includes 882 reactions, associated with 669 genes, and 790 metabolites. The model includes a detailed biomass equation which encompasses elementary building blocks that are needed for cell growth, as well as a detailed stoichiometri

SUBMITTER: Montagud A 

PROVIDER: S-EPMC3009638 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature