Nucleophilic Aromatic Substitution, A Guided Inquiry Laboratory Experiment.

ABSTRACT: Inquiry-based learning is a unique student-centered alternative to traditional instruction. This form of active learning is ideal for the organic chemistry laboratory as it encourages critical thinking and hands on problem solving to complete an experiment. Electrophilic Aromatic Substitution is immediately associated with the undergraduate organic chemistry course. However, nucleophilic aromatic substitution is not. The N-arylation of aniline derivatives is a useful reaction for implementing nucleophilic aromatic substitution into the undergraduate curriculum. Under the framework of inquiry-based learning, a straightforward procedure has been developed for the undergraduate laboratory. This experiment explores the reaction rate of the nucleophilic aromatic substitution using various elect

SUBMITTER: Winfield LL 

PROVIDER: S-EPMC3011185 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature