Cost-effectiveness of pre-referral antimalarial, antibacterial, and combined rectal formulations for severe febrile illness.

ABSTRACT:

Background

Malaria and bacterial infections account for most infectious disease deaths in developing countries. Prompt treatment saves lives, but rapid deterioration often prevents the use of oral therapies; delays in reaching health facilities providing parenteral interventions are common. Rapidly and reliably absorbed antimalarial/antibacterial rectal formulations used in the community could prevent deaths and disabilities. Rectal antimalarial treatments are currently available; rectal antibacterial treatments are yet to be developed. Assessment of the likely cost-effectiveness of these interventions will inform research priorities and implementation.

Methods and findings

The burden of malaria and bacterial infections worldwide and in Sub-Saharan and Southern Africa (SSA)

SUBMITTER: Buchanan J 

PROVIDER: S-EPMC3012053 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature