Bihemispheric brain stimulation facilitates motor recovery in chronic stroke patients.

ABSTRACT:

Objective

Motor recovery after stroke depends on the integrity of ipsilesional motor circuits and interactions between the ipsilesional and contralesional hemispheres. In this sham-controlled randomized trial, we investigated whether noninvasive modulation of regional excitability of bilateral motor cortices in combination with physical and occupational therapy improves motor outcome after stroke.

Methods

Twenty chronic stroke patients were randomly assigned to receive 5 consecutive sessions of either 1) bihemispheric transcranial direct current stimulation (tDCS) (anodal tDCS to upregulate excitability of ipsilesional motor cortex and cathodal tDCS to downregulate excitability of contralesional motor cortex) with simultaneous physical/occupational therapy or 2) sham stimula

SUBMITTER: Lindenberg R 

PROVIDER: S-EPMC3013585 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature