PhEVER: a database for the global exploration of virus-host evolutionary relationships.

ABSTRACT: Fast viral adaptation and the implication of this rapid evolution in the emergence of several new infectious diseases have turned this issue into a major challenge for various research domains. Indeed, viruses are involved in the development of a wide range of pathologies and understanding how viruses and host cells interact in the context of adaptation remains an open question. In order to provide insights into the complex interactions between viruses and their host organisms and namely in the acquisition of novel functions through exchanges of genetic material, we developed the PhEVER database. This database aims at providing accurate evolutionary and phylogenetic information to analyse the nature of virus-virus and virus-host lateral gene transfers. PhEVER (http://pbil.univ-lyon1.fr/dat

SUBMITTER: Palmeira L 

PROVIDER: S-EPMC3013642 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature