TIARA: a database for accurate analysis of multiple personal genomes based on cross-technology.

ABSTRACT: High-throughput genomic technologies have been used to explore personal human genomes for the past few years. Although the integration of technologies is important for high-accuracy detection of personal genomic variations, no databases have been prepared to systematically archive genomes and to facilitate the comparison of personal genomic data sets prepared using a variety of experimental platforms. We describe here the Total Integrated Archive of Short-Read and Array (TIARA; http://tiara.gmi.ac.kr) database, which contains personal genomic information obtained from next generation sequencing (NGS) techniques and ultra-high-resolution comparative genomic hybridization (CGH) arrays. This database improves the accuracy of detecting personal genomic variations, such as SNPs, short indels an

SUBMITTER: Hong D 

PROVIDER: S-EPMC3013693 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature