Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysis.

ABSTRACT:

Background

Depression is a common condition that has been frequently treated with psychotropics.

Aims

To review systematically the evidence of efficacy and acceptability of antidepressant and benzodiazepine treatments for patients with minor depression.

Method

A systematic review and meta-analysis of double-blind randomised controlled trials comparing antidepressants or benzodiazepines v. placebo in adults with minor depression. Data were obtained from MEDLINE, CINAHL, EMBASE, PsycInfo, Cochrane Controlled Trials Register and pharmaceutical company websites. Risk of bias was assessed for the generation of the allocation sequence, allocation concealment, masking, incomplete outcome data, and sponsorship bias.

Results

Six studies met inclusion criteria. Three stu

SUBMITTER: Barbui C 

PROVIDER: S-EPMC3014462 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature