Relation of worsened renal function during hospitalization for heart failure to long-term outcomes and rehospitalization.

ABSTRACT: Worsened renal function (WRF) during heart failure (HF) hospitalization is associated with in-hospital mortality, but there are limited data regarding its relation to long-term outcomes after discharge. The influence of WRF resolution is also unknown. This retrospective study analyzed patients who received care from a large health system and had a primary hospital discharge diagnosis of HF from January 2000 to June 2008. Renal function was estimated from creatinine levels during hospitalization. The first available value was considered baseline. WRF was defined a creatinine increase ≥ 0.3 mg/dl on any subsequent hospital day compared to baseline. Persistent WRF was defined as having WRF at discharge. Proportional hazards regression, adjusting for baseline renal function and potential confo

SUBMITTER: Lanfear DE 

PROVIDER: S-EPMC3016846 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature