Retinal and optic nerve head pathology in Susac's syndrome.

ABSTRACT:

Purpose

This article describes the first retinal histopathologic findings in a patient with Susac's syndrome (SS).

Design

Observational case report.

Participant

A 51-year-old white woman diagnosed with SS.

Methods

Eyes from a 51-year-old white woman diagnosed with SS were obtained at autopsy. One retina was dissected and processed for adenosine diphosphatase (ADPase) flat embedding. Selected areas were processed further for transmission electron microscopy.

Main outcome measures

Histopathologic examination using ADPase flat-embedding technique.

Results

There were vaso-occlusive changes in the retinal periphery resulting in small areas of capillary dropout. Cross-sections demonstrated serous filled spaces between the retinal blood vessels and the i

SUBMITTER: McLeod DS 

PROVIDER: S-EPMC3017218 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature