Visualization of the protein-coding regions with a self adaptive spectral rotation approach.

ABSTRACT: Identifying protein-coding regions in DNA sequences is an active issue in computational biology. In this study, we present a self adaptive spectral rotation (SASR) approach, which visualizes coding regions in DNA sequences, based on investigation of the Triplet Periodicity property, without any preceding training process. It is proposed to help with the rough coding regions prediction when there is no extra information for the training required by other outstanding methods. In this approach, at each position in the DNA sequence, a Fourier spectrum is calculated from the posterior subsequence. Following the spectrums, a random walk in complex plane is generated as the SASR's graphic output. Applications of the SASR on real DNA data show that patterns in the graphic output reveal locations o

SUBMITTER: Chen B 

PROVIDER: S-EPMC3017620 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature