Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants.

ABSTRACT:

Background

Peanut allergy is typically severe, lifelong, and prevalent.

Objective

To identify factors associated with peanut sensitization.

Methods

We evaluated 503 infants 3 to 15 months of age (mean, 9.4 months) with likely milk or egg allergy but no previous diagnosis of peanut allergy. A total of 308 had experienced an immediate allergic reaction to cow's milk and/or egg, and 204 had moderate to severe atopic dermatitis and a positive allergy test to milk and/or egg. A peanut IgE level ≥5 kU(A)/L was considered likely indicative of peanut allergy.

Results

A total of 140 (27.8%) infants had peanut IgE levels ≥5 kU(A)/L. Multivariate analysis including clinical, laboratory, and demographic variables showed frequent peanut consumption during pregnancy (odds ra

SUBMITTER: Sicherer SH 

PROVIDER: S-EPMC3018157 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature