Genomic differentiation between temperate and tropical Australian populations of Drosophila melanogaster.

ABSTRACT: Determining the genetic basis of environmental adaptation is a central problem of evolutionary biology. This issue has been fruitfully addressed by examining genetic differentiation between populations that are recently separated and/or experience high rates of gene flow. A good example of this approach is the decades-long investigation of selection acting along latitudinal clines in Drosophila melanogaster. Here we use next-generation genome sequencing to reexamine the well-studied Australian D. melanogaster cline. We find evidence for extensive differentiation between temperate and tropical populations, with regulatory regions and unannotated regions showing particularly high levels of differentiation. Although the physical genomic scale of geographic differentiation is small--on the ord

SUBMITTER: Kolaczkowski B 

PROVIDER: S-EPMC3018305 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature