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ABSTRACT: Context
Older patients with depression and executive dysfunction represent a population with significant disability and a high likelihood of failing pharmacotherapy.Objectives
To examine whether problem-solving therapy (PST) reduces disability more than does supportive therapy (ST) in older patients with depression and executive dysfunction and whether this effect is mediated by improvement in depressive symptoms.Design
Randomized controlled trial.Setting
Weill Cornell Medical College and University of California at San Francisco.Participants
Adults (aged >59 years) with major depression and executive dysfunction recruited between December 2002 and November 2007 and followed up for 36 weeks. Intervention Twelve sessions of PST modified for older depr
SUBMITTER: Alexopoulos GS
PROVIDER: S-EPMC3018861 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature