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The kinome of Phytophthora infestans reveals oomycete-specific innovations and links to other taxonomic groups.


ABSTRACT:

Background

Oomycetes are a large group of economically and ecologically important species. Its most notorious member is Phytophthora infestans, the cause of the devastating potato late blight disease. The life cycle of P. infestans involves hyphae which differentiate into spores used for dispersal and host infection. Protein phosphorylation likely plays crucial roles in these stages, and to help understand this we present here a genome-wide analysis of the protein kinases of P. infestans and several relatives. The study also provides new insight into kinase evolution since oomycetes are taxonomically distant from organisms with well-characterized kinomes.

Results

Bioinformatic searches of the genomes of P. infestans, P. ramorum, and P. sojae reveal they have similar kinomes,

SUBMITTER: Judelson HS 

PROVIDER: S-EPMC3019232 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature