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Complete genome sequence of adherent invasive Escherichia coli UM146 isolated from Ileal Crohn's disease biopsy tissue.

ABSTRACT: Escherichia coli UM146 was isolated from the ileum of a Crohn's disease patient. It adheres to and invades enterocytes and can replicate inside macrophages. Its complete genome sequence reveals that it is most closely related to the human urinary tract pathogen E. coli CFT073, but it has a host of genes that are novel and to which no function has been ascribed.

SUBMITTER: Krause DO 

PROVIDER: S-EPMC3019814 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Complete genome sequence of adherent invasive Escherichia coli UM146 isolated from Ileal Crohn's disease biopsy tissue.

Krause Denis O DO   Little Ainsley C AC   Dowd Scot E SE   Bernstein Charles N CN  

Journal of bacteriology 20101112 2

Escherichia coli UM146 was isolated from the ileum of a Crohn's disease patient. It adheres to and invades enterocytes and can replicate inside macrophages. Its complete genome sequence reveals that it is most closely related to the human urinary tract pathogen E. coli CFT073, but it has a host of genes that are novel and to which no function has been ascribed. ...[more]

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